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Applications of mass spectrometry to metabolomics and metabonomics: Detection of biomarkers of aging and of age-related diseases

Robert J. Mishur, Shane L. Rea

Journal:

Mass Spectrometry Reviews

Année:

2012

Langue:

english

Fichier:

PDF, 658 KB

english, 2012

33 Biomarkers of mitochondrial dysfunction—Distinct metabolomic profiles differentiate long-lived from short-lived mitochondrial mutants in C. elegans

Jeffrey Butler, Shane L. Rea

Journal:

Mitochondrion

Année:

2010

Langue:

english

Fichier:

PDF, 46 KB

english, 2010

Post-Younger Dryas seasonality in the North American midcontinent region as recorded in Lake Huron varved sediments

Godsey, Holly S, Moore, Jr., Theodore C, Rea, David K, Shane, Linda CK

Journal:

Canadian Journal of Earth Sciences

Année:

1999

Fichier:

PDF, 1.55 MB

1999

The role of mitochondrial dysfunction in age-related diseases

Lane, Rebecca K., Hilsabeck, Tyler, Rea, Shane L.

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Année:

2015

Langue:

english

Fichier:

PDF, 821 KB

english, 2015

Mitochondrial metabolites extend lifespan

Mishur, Robert J., Khan, Maruf, Munkácsy, Erin, Sharma, Lokendra, Bokov, Alex, Beam, Haley, Radetskaya, Oxana, Borror, Megan, Lane, Rebecca, Bai, Yidong, Rea, Shane L.

Journal:

Aging Cell

Année:

2016

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2016

Bacteria, yeast, worms, and flies: Exploiting simple model organisms to investigate human mitochondrial diseases

Shane L. Rea, Brett H. Graham, Eiko Nakamaru-Ogiso, Adwitiya Kar, Marni J. Falk

Journal:

Development Diabilities Research Reviews

Année:

2010

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2010

Breaking Caenorhabditis elegans the easy way using the Balch homogenizer: An old tool for a new application

Shylesh Bhaskaran, Jeffrey A. Butler, Sandra Becerra, Veronica Fassio, Milena Girotti, Shane L. Rea

Journal:

Analytical Biochemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.00 MB

english, 2011

Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans

Natascia Ventura, Shane Rea, Samuel T. Henderson, Ivano Condo, Thomas E. Johnson, Roberto Testi

Journal:

Aging Cell

Année:

2005

Langue:

english

Fichier:

PDF, 120 KB

english, 2005

Mortality shifts in Caenorhabditis elegans: remembrance of conditions past

Deqing Wu, Shane L. Rea, James R. Cypser, Thomas E. Johnson

Journal:

Aging Cell

Année:

2009

Langue:

english

Fichier:

PDF, 447 KB

english, 2009

p53/CEP-1 increases or decreases lifespan, depending on level of mitochondrial bioenergetic stress

Natascia Ventura, Shane L. Rea, Alfonso Schiavi, Alessandro Torgovnick, Roberto Testi, Thomas E. Johnson

Journal:

Aging Cell

Année:

2009

Langue:

english

Fichier:

PDF, 736 KB

english, 2009

A stress-sensitive reporter predicts longevity in isogenic populations of Caenorhabditis elegans

Rea, Shane L, Wu, Deqing, Cypser, James R, Vaupel, James W, Johnson, Thomas E

Journal:

Nature Genetics

Année:

2005

Langue:

english

Fichier:

PDF, 296 KB

english, 2005

Caenorhabditis elegans mitochondrial mutants as an investigative tool to study human neurodegenerative diseases associated with mitochondrial dysfunction

Natascia Ventura, Shane L. Rea

Journal:

Biotechnology Journal

Année:

2007

Langue:

english

Fichier:

PDF, 457 KB

english, 2007

Metabolism in the Caenorhabditis elegans Mit mutants

Shane L. Rea

Journal:

Experimental Gerontology

Année:

2005

Langue:

english

Fichier:

PDF, 150 KB

english, 2005

Corrigendum to “Metabolism in the Caenorhabditis elegans Mit mutants” [Experimental Gerontology 40 (2005) 841–849]

Shane L. Rea

Journal:

Experimental Gerontology

Année:

2006

Fichier:

PDF, 40 KB

2006

Visualizing hidden heterogeneity in isogenic populations of C. elegans

Deqing Wu, Shane L. Rea, Anatoli I. Yashin, Thomas E. Johnson

Journal:

Experimental Gerontology

Année:

2006

Langue:

english

Fichier:

PDF, 198 KB

english, 2006

Long-lived C. elegans Mitochondrial mutants as a model for human mitochondrial-associated diseases

Natascia Ventura, Shane L. Rea, Roberto Testi

Journal:

Experimental Gerontology

Année:

2006

Langue:

english

Fichier:

PDF, 339 KB

english, 2006

Why only time will tell

Siegfried Hekimi, Claire Bénard, Robyn Branicky, Jason Burgess, Abdelmadjid K. Hihi, Shane Rea

Journal:

Mechanisms of Ageing and Development

Année:

2001

Langue:

english

Fichier:

PDF, 392 KB

english, 2001

Botulinum E Toxin Light Chain Does Not Cleave SNAP-23 and Only Partially Impairs Insulin Stimulation of GLUT4 Translocation in 3T3-L1 Cells

S.Lance Macaulay, Shane Rea, Keith H. Gough, Colin W. Ward, David E. James

Journal:

Biochemical and Biophysical Research Communications

Année:

1997

Langue:

english

Fichier:

PDF, 505 KB

english, 1997

The role of MAP4K3 in lifespan regulation of Caenorhabditis elegans

Maruf H. Khan, Matthew J. Hart, Shane L. Rea

Journal:

Biochemical and Biophysical Research Communications

Année:

2012

Langue:

english

Fichier:

PDF, 603 KB

english, 2012

CLK-1/Coq7p is a DMQ mono-oxygenase and a new member of the di-iron carboxylate protein family

Shane Rea

Journal:

FEBS Letters

Année:

2001

Langue:

english

Fichier:

PDF, 337 KB

english, 2001

Corrigendum to: CLK-1/Coq7p is a DMQ mono-oxygenase and a new member of the di-iron carboxylate protein family (FEBS 25488): [FEBS Letters 509 (2001) 389–394]

Shane Rea

Journal:

FEBS Letters

Année:

2002

Fichier:

PDF, 24 KB

2002

A Metabolic Model for Life Span Determination in Caenorhabditis elegans

Shane Rea, Thomas E. Johnson

Journal:

Developmental Cell

Année:

2003

Langue:

english

Fichier:

PDF, 194 KB

english, 2003

Younger Dryas Interval and outflow from the Laurentide Ice Sheet

Moore, T. C., Walker, J. C. G., Rea, D. K., Lewis, C. F. M., Shane, L. C. K., Smith, A. J.

Journal:

Paleoceanography

Année:

2000

Langue:

english

Fichier:

PDF, 1.83 MB

english, 2000

A metabolic signature for long life in the Caenorhabditis elegans Mit mutants

Butler, Jeffrey A., Mishur, Robert J., Bhaskaran, Shylesh, Rea, Shane L.

Journal:

Aging Cell

Année:

2013

Langue:

english

Fichier:

PDF, 869 KB

english, 2013

The paradox of mitochondrial dysfunction and extended longevity

Munkácsy, Erin, Rea, Shane L.

Journal:

Experimental Gerontology

Année:

2014

Langue:

english

Fichier:

PDF, 761 KB

english, 2014

Proteasomal dysfunction activates the transcription factor SKN-1 and produces a selective oxidative-stress response in Caenorhabditis elegans

Kahn, Nate W., Rea, Shane L., Moyle, Sarah, Kell, Alison, Johnson, Thomas E.

Journal:

Biochemical Journal

Année:

2008

Langue:

english

Fichier:

PDF, 490 KB

english, 2008

Correction: Relationship Between Mitochondrial Electron Transport Chain Dysfunction, Development, and Life Extension in Caenorhabditis elegan

Rea, Shane L., Ventura, Natascia, Johnson, Thomas E.

Journal:

PLoS Biology

Année:

2008

Langue:

english

Fichier:

PDF, 42 KB

english, 2008

Relationship Between Mitochondrial Electron Transport Chain Dysfunction, Development, and Life Extension in Caenorhabditis elegans

Rea, Shane L., Ventura, Natascia, Johnson, Thomas E.

Journal:

PLoS Biology

Année:

2007

Langue:

english

Fichier:

PDF, 47 KB

english, 2007

Correction: Relationship Between Mitochondrial Electron Transport Chain Dysfunction, Development and Life Extension in Caenorhabditis elegans

Rea, Shane L., Ventura, Natascia, Johnson, Thomas E.

Journal:

PLoS Biology

Année:

2008

Langue:

english

Fichier:

PDF, 46 KB

english, 2008

Identification of a regulatory function for an orphan receptor in muscle: COUP-TF II affects the expression of the myoD gene family during myogenesis

Muscat, George E. O., Rea, Shane, Downes, Michael

Journal:

Nucleic Acids Research

Année:

1995

Langue:

english

Fichier:

PDF, 850 KB

english, 1995

Histiocytoid cardiomyopathy and microphthalmia with linear skin defects syndrome: phenotypes linked by truncating variants in NDUFB11

Rea, Gillian, Homfray, Tessa, Till, Jan, Roses-Noguer, Ferran, Buchan, Rachel J., Wilkinson, Sam, Wilk, Alicja, Walsh, Roddy, John, Shibu, McKee, Shane, Stewart, Fiona J., Murday, Victoria, Taylor, Ro

Journal:

Molecular Case Studies

Année:

2017

Langue:

english

Fichier:

PDF, 1.59 MB

english, 2017

209 Whole Exome Sequencing Identifies Genetic Cause of Histiocytoid Cardiomyopathy

Rea, Gillian, Homfray, Tessa, Till, Jan, Roses-Noguer, Ferran, Buchan, Rachel J, Wilkinson, Sam, Walsh, Roddy, McKee, Shane, Stewart, Fiona J, Murday, Victoria, Taylor, Robert W, John Baksi, A, Prasad

Journal:

Heart

Année:

2016

Langue:

english

Fichier:

PDF, 862 KB

english, 2016

P35 Histiocytoid cardiomyopathy and microphthalmia with linear skin defects syndrome: Phenotypes linked by truncating variants in NDUFB11

Rea, Gillian, Ware, James S, Homfray, Tessa, Till, Jan, Roses-Noguer, Ferran, Buchan, Rachel, Wilkinson, Sam, Wilk, Alicja, Walsh, Roddy, John, Shibu, McKee, Shane, Stewart, Fiona J, Murday, Victoria,

Journal:

Heart

Année:

2016

Langue:

english

Fichier:

PDF, 58 KB

english, 2016

DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans

Munkácsy, Erin, Khan, Maruf H., Lane, Rebecca K., Borror, Megan B., Park, Jae H., Bokov, Alex F., Fisher, Alfred L., Link, Christopher D., Rea, Shane L., Kim, Stuart K.

Journal:

PLoS Genetics

Année:

2016

Langue:

english

Fichier:

PDF, 12.14 MB

english, 2016

CLD1 Reverses the Ubiquinone Insufficiency of Mutant cat5/coq7 in a Saccharomyces cerevisiae Model System

Kar, Adwitiya, Beam, Haley, Borror, Megan B., Luckow, Michael, Gao, Xiaoli, Rea, Shane L., Bryk, Mary

Journal:

PLoS ONE

Année:

2016

Langue:

english

Fichier:

PDF, 3.71 MB

english, 2016

BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans

Torgovnick, Alessandro, Schiavi, Alfonso, Shaik, Anjumara, Kassahun, Henok, Maglioni, Silvia, Rea, Shane L, Johnson, Thomas E, Reinhardt, Hans C, Honnen, Sebastian, Schumacher, Björn, Nilsen, Hilde, V

Journal:

EMBO reports

Année:

2018

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2018